History of Sequencing (with a focus on more recent developments)
Main reading:
Alternative readings
- http://www.
microbialinformaticsj.com/ content/2/1/3/ - http://www.hindawi.com/
journals/bmri/2012/251364/abs/ - http://m.
cancerpreventionresearch. aacrjournals.org/content/5/7/ 887.full
Also check out
Youtube videos of relevance
Outline and Notes
- Timeline of DNA sequencing
- Generation I: Manual sequencing
- Maxam – Gilbert
- Sanger
- Some details on Sanger
- Generation I+: Automation
- Capillary / fluorescent Sanger
- Colony picking robotics
- Highlights
- Generation II: Colonies not Clones