Global Grand Challenges projects on antimicrobial resistance

The winners of the Bill & Melinda Gates Foundation Global Grand Challenges Round 16 were announced recently. Among the challenge topics included in this round of competition was Novel Approaches to Characterizing and Tracking the Global Burden of Antimicrobial Resistance. The Gates Foundation made six awards in this topic area: Christopher Mason of Cornell University (USA) will generate a global …

The CDC’s MicrobeNet now includes MALDI-TOF MS data

microBE.net is an awesome name, so I wasn’t that surprised to find that the CDC has it’s own MicrobeNet that they launched in 2013. MicrobeNet is a free online curated database of emerging bacteria and fungi that aims to improve reference diagnostics and pathogen identification. The database includes genetic sequence data (16S rRNA), biochemical data, morphological characteristics and antibiotic resistance profiles for about 2,400 species, as well …

International conference on the use of antibiotics in animals

The 4th International Conference on Responsible Use of Antibiotics in Animals is scheduled for 26-28 September in the Hague, the Netherlands. This is an important and timely topic with federal regulations changing current agricultural practices. Here is some information from the conference website: Antibiotics are used worldwide both in veterinary and human medicine. The widespread …

Probiotics for Livestock – Reducing Antibiotic Reliance

In the wake of the Obama administration’s plan to decrease antibiotic usage in livestock, farmers are now trying to find alternatives that have fewer ecological and human health impacts. In an effort to reduce reliance on antibiotics, researchers at Iowa State University are testing if Lactobacillus species found in yogurt might have a similar health effect on livestock as …

Tilikum to Shed Light on Superbug Crisis?

You have all heard of Tilikum the killer whale. He’s known for killing 3 of his trainers and is featured in the documentary Blackfish. Regardless of where you stand in all of the controversy, Tilikum has been making the news once again due to an untreatable bacterial infection in his lungs. Here is the statement from SeaWorld: …

Journal Club: Antibiotics in Agroecosystems

A great review has come out on the use and ramifications of antibiotics in agroecosystems. “Antibiotics in Agroecosystems: Introduction to the Special Section” by Allison Frankiln et al is a review that attempts to get everyone on the same page about antibiotics, antibiotic resistant bacteria, and antibiotic resistant genes in the environment. The article highlights …

How to Deal with Superbugs in Waste Treatment Facilities

The Los Angeles Times posted an article yesterday on “Deadly superbugs from hospitals get stronger in the sewers and could end up in the Pacific Ocean”. While there is some truth to the matter, it is necessary to approach it with some skepticism. It is well known that antibiotic resistant bacteria are extremely prevalent in …

Antibiotics Susceptibility Pattern of Hospital Indoor Airborne Bacteria

Jonathan drew my attention to this paper on antibiotic susceptibility of 153 bacterial isolates collected from a hospital in Ethiopia. I thought the numerous grammatical errors in the paper would parallel with the quality of the study, but I was pleasantly disproved. In the abstract they state, “86.9% [of the 153 isolates] were resistant to …

Electron Microscopy and Fighting Superbugs

Last week, a bunch of news articles came out (like this one) that talk about how we are on track to figuring out new ways to tackle antibiotic resistant superbugs. The research they are referring to highlights a paper recently published in Nature (a closed access journal) by Changjiang Dong’s group at the University of East …

Blueprinting a New Antimicrobial

This recent news article discusses a new candidate antimicrobial called Globomycin and the work that researchers at  Trinity College Dublin have put in to map out its spatial organization. A particularly interesting point that is discussed is the idea of narrow-spectrum antibiotics. Antibiotic/antimicrobial resistance is driven in part by the fact that these drugs target a …