Important paper: Intrinsic challenges in ancient microbiome reconstruction using 16S rRNA gene amplification

To date, characterization of ancient oral (dental calculus) and gut (coprolite) microbiota has been primarily accomplished through a metataxonomic approach involving targeted amplification of one or more variable regions in the 16S rRNA gene. For anyone interested in rRNA studies of microbial communities, ancient microbiomes, or analysis of samples with small amounts of DNA this …

Gearing up the UNITE database for the built mycobiome

Gearing up the UNITE database for the built mycobiome The team behind the UNITE database for molecular identification of fungi has been granted support from the Sloan Foundation to strengthen the support for fungi from the built environment. Launched in 2001 as an ITS database for identification of ectomycorrhizal fungi in the Nordic countries, UNITE …

A Novel Approach to Combating Antibiotic Resistance?

It is well known that antibiotic resistance in bacteria happens much faster than we can possibly develop novel antibiotics. So what if instead of trying to reinvent the wheel, we just rearrange it? Well, researchers at the H. Lee Moffitt Cancer Center and Research Institute had a similar idea in regards to reducing antibiotic resistance …

Wrap up of talk by Norm Pace on “Metagenomics and the Tree of Life”

Norm Pace gave a talk at UC Davis yesterday on “Metagenomics and the Tree of Life”. I and a few other people posted live Tweets from the talk which I have compiled together via the Storify system.  This “Storify” is embedded below. In addition, Lisa Cohen, who was at the talk posted her notes which …

Nominations sought for NAS Committee on Microbiomes of the Built Environment

Just got sent this by Katherine Bowman from the Board on Life Sciences.  This is really important and if you know of someone who would be good please consider nominating them.     Request for Committee Nominations — Microbiomes of the Built Environment: From Research to Application The National Academies of Sciences, Engineering, and Medicine are …

Request for comments on scikit-bio: should we drop support for Python 2 in favor of Python 3 only?

scikit-bio is a library implementing core bioinformatics algorithms and data structures, and providing support for bioinformatics data munging. You can learn more about the project by watching Jai Rideout and Evan Bolyen’s 20 minute SciPy 2015 talk. scikit-bio currently supports Python 2 (i.e., Legacy Python) and Python 3. We’re considering dropping support for Python 2, …

Behind the paper: 16Stimator

In scientific manuscripts, we tell stories of our research, generally in straight-line fashion with clear motivations and results. This type of research is rare (in my experience), with stories, motivations, and applications only realized post hoc. This is the nature of science, and our recent ISMEJ publication is no different. With “16Stimator: statistical estimation of …