Development of antibiotic resistance under simulated microgravity

So just a quick post about this new paper “Evaluation of Acquired Antibiotic Resistance in Escherichia coli Exposed to Long-Term Low-Shear Modeled Microgravity and Background Antibiotic Exposure“.   Seems pretty straightforward… 1000 generations of E. coli in simulated microgravity… expose them to antibiotics and study the development of resistance.   This is in contrast to some previous …

NASEM Webinar “Microbiome, Wastewater Treatment, and Antibiotic Resistance” 9/25/18

Just got this e-mail regarding an upcoming NASEM Webinar “Microbiome, Wastewater Treatment, and Antibiotic Resistance” on 9/25/18.  Here’s the description of the event: In 2017, the National Academies of Sciences, Engineering and Medicine released the report, Microbiomes of the Built Environment: A Research Agenda for Indoor Microbiology, Human Health, and Buildings. The report highlights the importance …

This air resistance is a real drag: global survey of antibiotic resistance genes in air samples

This new open access paper from Li et al may be of interest. Global Survey of Antibiotic Resistance Genes in Air.   Abstract: Despite its emerging significant public health concern, the presence of antibiotic resistance genes (ARGs) in urban air has not received significant attention. Here, we profiled relative abundances (as a fraction, normalized by 16S rRNA …

Paper of interest: Predicting antibiotic resistance from full genome sequences 

This preprint seems like it may be of interest to folks: Precise prediction of antibiotic resistance in Escherichia coli from full genome sequences | bioRxiv Basically, the authors showed that, using a machine learning approach, they can quite accurately predict antibiotic resistance in E. coli from whole genome data. The emergence of microbial antibiotic resistance …

Paper of interest: antibiotic resistance and the safety of reusing treated wastewater

Paper of possible interest: Hong, P.-Y.; Julian, T.R.; Pype, M.-L.; Jiang, S.C.; Nelson, K.L.; Graham, D.; Pruden, A.; Manaia, C.M. Reusing Treated Wastewater: Consideration of the Safety Aspects Associated with Antibiotic-Resistant Bacteria and Antibiotic Resistance Genes. Water 2018, 10, 244. Abstract: As more countries engage in water reuse, either intended or de facto, there is …

New paper of interest on antibiotic resistance genes in 4 CA cities but dangerous PR from UCLA

This new paper may be of interest: Source: Disparate Antibiotic Resistance Gene Quantities Revealed across 4 Major Cities in California: A Survey in Drinking Water, Air, and Soil at 24 Public Parks – ACS Omega (ACS Publications) Abstract: Widespread prevalence of multidrug and pandrug-resistant bacteria has prompted substantial concern over the global dissemination of antibiotic …

Your help is wanted in this #CitizenMicrobiology project: “BashTheBug – Help us fight antibiotic resistance!”

Just found out about this new Citizen Microbiology project via Andrew Su on Twitter who retweeted a post of Jennifer Gardy’s A neat citizen science project launched today as part of the big TB sequencing consortium -help spot drug resistance https://t.co/rFHsrmdBJk — Jennifer Gardy (@jennifergardy) April 7, 2017 Source: BashTheBug – Help us fight antibiotic resistance! …

Job: antibiotic resistance in 100k TB genomes

Hi All I’d just like to highlight a job we are advertising, to lead the bioinformatic (sequence+variation) analysis of 100,000 M tuberculosis genomes which we are sequencing (WGS), ~50,000 of which will be phenotyped for 12 drugs, and the remainder for some subset. Note the deadline is very soon – Monday 6th March! This project …

Koala Poop Microbiome Class: Week 10, Antibiotic Resistance Measurements

Since this was the last week of the quarter, we didn’t require the students to blog as in the previous 9 weeks.  Also, mostly we recapped what had happened in the class and discussed various assignments.  But the students did measure the antibiotic resistance of their strains, and we also had a powerful demonstration of …

Koala Poop Microbiome Class: Week 9, Antibiotic Resistance

(This blog post was prepared by students enrolled in the Koala Poop Microbiome Class in the Fall of 2016 at UC Davis) This week we focused on antibiotic sensitivity on the individual bacteria that were identified last week. The day before class, the bacteria that we have been working with all quarter were recultured in …