Thinking about microbial quantity and function

One of the hurdles in linking microbial ecology with building science has been incorporating quantitative information about the microorganisms encountered in indoor environments, mainly because the standard high-throughput amplicon approach for community analysis is semi-quantitative, at best. Over the summer, there was a Twitter conversation related to this topic. My take-away from this (what I view …

New Release! Infectious Diseases in the Urban Built Environment Proceedings of a Workshop

On June 8, the National Academies Press released a proceedings of a workshop on Urbanization and Slums: Infectious Diseases in the Built Environment, available for free download here. The workshop rapporteurs have prepared this proceedings as a factual summation of the sessions presented by the National Academies’ Forum on Microbial Threats, in collaboration with the Board …

Fuzzy zeros in percentile normalization method to correct for batch effects

We recently published a method to normalize data that corrects for batch effects and allows for pooling of raw data across studies. In this post, I want to discuss more about the important (but potentially confusing) aspect of our method, where we add noise to the zeros before performing the normalization. I’ve gotten a few …

4th Annual MetaSUB Conference (Aug. 14-15) and Call for Abstracts

We are excited to announce the MetaSUB International Consortium’s 4th Annual Conference on urban metagenomics to be held at the Tivoli Ecoresort Praia do Forte Bahia in Brazil, from August 14-15, 2018. The conference is co-hosted by Weill Cornell Medicine and the AC Camargo Cancer Center. You can register for the meeting here: http://metasub.org/metasub-2018-conference-registration-form/ If you’d …