Journal Club: Metagenomics on the Space Station

Microbes in space have been of interest to the folks at various space agencies for as long as we’ve been sending people into space.  Rampant mold growth on the Russian Space Station Mir was probably one of the reasons for the decision to “deorbit” the station (a fancy way of describing crashing into the ocean).  …

What is the Exposome of the Built Environment and What are the Opportunities for Intentional Design?

  Researchers at Virginia Tech’s Center for Science and Engineering of the Exposome (SEE) recently published a critical review in ES&T examining the “exposome of the built environment” and proposed engineering strategies for its control. The exposome is defined as our lifetime exposure to chemicals, microbes, and radiation and derives from anything we come into …

Has “The antibiotic course” had its day? Some say yes, some say no or not yet 

“Should we always antibiotics until the end of their course?” Well, this has been a question asked on and off over the last 10 years or so.  And this I was quite interested in a Tweet I saw from Eric Topol this AM (I note – Eric Topol on Twitter is a better source of …

Should we change the threshold for statistical significance? Many think so ..

There is a new preprint that was posted recently in the PsyArXiv that may (or even should) be of interest: Redefine statistical significance by Benjamin al. One sentence summary from the authors: We propose to change the default P-value threshold for statistical significance for claims of new discoveries from 0.05 to 0.005. First page or so: …

Superbugs Phone Game and Longitude Prize Competition #Resistance

This looks pretty cool Source: Superbugs | Longitude Prize From their site Destroy deadly bacteria and keep humanity’s precious antibiotics working for as long as you can in this free, fast-paced, and addictive action game. The story of this casual, real-time puzzle game comes straight from today’s headlines: The rise of superbugs, resistant bacteria which …

Everyone should read this piece by Ed Yong: Norm Pace Blew The Door Off The Microbial World

There is a wonderful tribute to Norm Pace in the Atlantic by Ed Yong. Norm Pace truly did blow the door off the microbial world. Source: Norm Pace Blew The Door Off The Microbial World – The Atlantic Lots of good stuff in there about Pace and his career.  See for example this: Pace also …

An interesting idea – “The Genomics Education Alliance”

Just got an email pointing me to this White Paper on Figshare …… Seems like a worthy ambition and worth a look. Some key bits: Vision The rapid pace of scientific advancement presents a continuing challenge to effective life science education. The genomics revolution brings with it a unique challenge for the biology educator, as …

Worth a look: DNA Links Deadly Germs, Tainted Heart Surgery Devices To German Factory 

Quick post here. This is definitely worth a look for those interested in hospital acquired infections, microbial genomics, and genomic epidemiology or related topics. LivaNova plant in Germany is the likely source behind outbreak that has sickened more than 100 people since 2013. Source: DNA Links Deadly Germs, Tainted Heart Surgery Devices To German Factory …