This seems like it is a must read for anyone working on microbiomes: Frontiers | Microbiome Datasets Are Compositional: And This Is Not Optional | Microbiology Gloor GB, Macklaim JM, Pawlowsky-Glahn V and Egozcue JJ (2017) Microbiome Datasets Are Compositional: And This Is Not Optional. Front. Microbiol. 8:2224. doi: 10.3389/fmicb.2017.02224 Summary from the paper: Datasets …
The Brito Lab at Cornell University in Ithaca, NY works in the area of systems biology of the human microbiome. We are looking for talented postdocs to fill two open positions for postdoctoral researchers interested in investigating mechanistic linkages between microbes and human health outcomes. Postdoctoral candidates can have an experimental or computational background, or both. One of …
This new paper in PLOS Computational. Biology may be of interest: : The application of project-based learning in bioinformatics training by Emery LR and Morgan SL. Although many out there may already be doing projects based learning for bioinformatics, many others are not. This paper discusses how the authors added a projects component to an existing course …
Why use Bracken instead of Kraken? by Jennifer Lu and Steven Salzberg Kraken is a very fast, accurate program for classifying metagenomic sequencing data. It takes a set of reads, contigs, or other DNA sequences and for assigns a taxonomic label (species, genus, etc.) to each one. Last year we discovered that some people were …
[View the story “#NeLLi17 – From New Lineages of Life To New Functions Day 2” on Storify]
Hi All I’d just like to highlight a job we are advertising, to lead the bioinformatic (sequence+variation) analysis of 100,000 M tuberculosis genomes which we are sequencing (WGS), ~50,000 of which will be phenotyped for 12 drugs, and the remainder for some subset. Note the deadline is very soon – Monday 6th March! This project …
With our paper recently accepted for publication and many months of practical application, we’re excited to spread the word about our new tool for characterizing metagenomes, PALADIN! Short for Protein ALignment And Detection INterface, PALADIN was our response to the inherent problem of limited references in shotgun metagenomic sequencing. While DNA barcoding involving 16S, 18S, …
There is an increasing number of studies with a large number genomes recovered from isolate, metagenome, or single cell sequencing. To bridge the gap between the available genome sequences and available phenotype information, we have developed Traitar, a bioinformatics software to phenotype bacteria based on their genome sequence (see workflow below) . Traitar includes phenotype models for …
Here’s the report from Day 1 of the 5th annual Microbiology of the Built Environment meeting in Boulder, CO. Following my summary of the talks is a Storify of all the tweets from the day. The first talk of the day was by Ulla Haverinen-Shaughnessy from the University of Eastern Finland whose talk was entitled …
Do you think you can look at your microbiome or related data and detect patterns? Well, then this game may be for you: The 8-Bit Game That Makes Statistics Addictive Please make it stop. Nice article by Ed Yong in the Atlantic. But I warn you, don’t try it if you want to get …