Paper of possible interest: KatharoSeq Enables High-Throughput Microbiome Analysis from Low-Biomass Samples

This may be of interest to people out there.  Source: KatharoSeq Enables High-Throughput Microbiome Analysis from Low-Biomass Samples | mSystems Abstract: Microbiome analyses of low-biomass samples are challenging because of contamination and inefficiencies, leading many investigators to employ low-throughput methods with minimal controls. We developed a new automated protocol, KatharoSeq (from the Greek katharos [clean]), …

Postdoc Opportunity for Computational Microbial Ecologist in Seattle

  The Gibbons group at the Institute for Systems Biology (ISB) is seeking a computationally-oriented Postdoctoral Fellow with interests in microbial ecology, evolution, and human health. The successful applicant will work with an interdisciplinary team of microbiologists, systems biologists, bioinformaticians, and clinical researchers to:  Integrate and analyze multi-omic data from Arivale as part of the …

Help wanted: looking for a recent (post 2012) #openaccess review on molecular phylogenetic methods

I am getting ready for my “EVE161” class on Sequence based studies of the diversity of microbes.  For more about past versions of the class see here: https://www.microbe.net/eve161/. Anyway – I am working on the reading for the class and I am looking for a good, recent, open access review of molecular phylogenetic methods.  Any recommendations …

Why genome completeness and contamination estimates are more complicated than you think

Genome-resolved metagenomics is the process of recovering de novo genomes belonging to individual organisms present in a community using DNA extracted from the whole community. These genomes are sometimes referred to as MAGs (metagenome-assembled genomes), and are recovered by associating assembled contigs together in “bins” in a process known as genome binning. As opposed to …

Paper generating a lot of buzz: Nucleic acid purification from plants, animals and microbes in under 30 seconds

Well, this paper is generating a lot of buzz on social media.  Nucleic acid purification from plants, animals and microbes in under 30 seconds.  For example see Eric Topol’s Tweet about it Now this is innovative: paper dipstick extraction of DNA or RNA in < 30 seconds https://t.co/RKuLsAW7fM @PLOSBiology @UQ_News pic.twitter.com/FH1krTFYMw — Eric Topol (@EricTopol) …

Nice title, nice paper: Microbiome Datasets Are Compositional: And This Is Not Optional 

This seems like it is a must read for anyone working on microbiomes: Frontiers | Microbiome Datasets Are Compositional: And This Is Not Optional | Microbiology Gloor GB, Macklaim JM, Pawlowsky-Glahn V and Egozcue JJ (2017) Microbiome Datasets Are Compositional: And This Is Not Optional. Front. Microbiol. 8:2224. doi: 10.3389/fmicb.2017.02224 Summary from the paper: Datasets …

BE microbiome as biosensors

  Hi MoBE blog, I just wanted to share a piece that I recently wrote for a Special Issue on the journal Microbial Biotechnology. The Special issue presents a collection articles about “The contribution of microbial biotechnology to sustainable development goals”, and the title of my article is “Microbial communities as biosensors for monitoring urban …